Off-spinner Amit Jaggernauth and slow left-armer Sulieman Benn have been named in a 15-man squad.
Both have good records in Caribbean domestic cricket and have been given the chance to prove they can make the step up to international level
The two-match series begins in Guyana on 22 March, with the second game following on 3 April in Trinidad.
The squad has been shaken up following a tour to South Africa earlier this year when West Indies lost the Test series 2-1.
Batsmen Daren Ganga, Runako Morton and Brenton Parchment have all been left out, along with all-rounder Darren Sammy and leg-spinner Rawl Lewis.
Opener Sewnarine Chattergoon has been given his first chance in the Test squad after playing six one-day internationals and could partner captain Chris Gayle at the top of the order.
The selectors have also recalled Ryan Hinds, who made the last of his nine Test appearances so far three years ago.
Fellow all-rounder Marlon Samuels keeps his place but will have to play as a specialist batsman against Sri Lanka following last month's ruling that his bowling action is illegal.
Analysts discovered Samuels straightened his arm by an average of 27 degrees, compared to legal limit of 15 and he has been ordered to re-model his action.
West Indies squad: Chris Gayle (capt), Dwayne Bravo, Sulieman Benn, Sewnarine Chattergoon, Shivnarine Chanderpaul, Pedro Collins, Fidel Edwards, Ryan Hinds, Amit Jaggernauth, Darren Powell, Denesh Ramdin (wk), Marlon Samuels, Ramnaresh Sarwan, Devon Smith, Jerome Taylor.